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c-MYC 抗体 (AA 36-65)

This 兔 多克隆 antibody specifically detects c-MYC in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN3029539
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for c-MYC 抗体 (AA 36-65) (ABIN3029539)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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克隆类型

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多克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 36-65

    交叉反应 (详细)

    Expected species reactivity: Bovine, Chicken, Mouse, Pig, Rat, Xenopus, Zebrafish

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 36-65 from the human protein was used as the immunogen for this Myc antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Myc antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    Myc Proto-Oncogene protein

    背景

    MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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