MMP7 抗体 (AA 117-146)
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Quick Overview for MMP7 抗体 (AA 117-146) (ABIN3031723)
抗原
See all MMP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 117-146
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纯化方法
- Purified
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免疫原
- A portion of amino acids 117-146 from the human protein was used as the immunogen for this MMP7 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MMP7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MMP7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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别名
- MMP7
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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UniProt
- P09237
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途径
- Production of Molecular Mediator of Immune Response
抗原
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