MMP2 抗体 (AA 303-331)
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Quick Overview for MMP2 抗体 (AA 303-331) (ABIN3031729)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 303-331
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Chicken, Rabbit
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 303-331 from the human protein was used as the immunogen for this MMP2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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