MLH1 抗体 (AA 452-480)
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Quick Overview for MLH1 抗体 (AA 452-480) (ABIN3031882)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 452-480
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MLH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
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UniProt
- P40692
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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