MELK 抗体 (AA 381-415)
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北京 101111
Quick Overview for MELK 抗体 (AA 381-415) (ABIN3031706)
抗原
See all MELK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-415
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纯化方法
- Antigen affinity purified
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免疫原
- This mouse Melk antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 381-415 amino acids from the Central region of mouse Melk.
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亚型
- Ig Fraction
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anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody
MELK 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibodyMELK 适用: 人 ELISA, IHC, IF, FACS 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibodyMELK 适用: 人 ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 434-468), (C-Term) antibodyMELK 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB51204 unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibodyMELK 适用: 人 IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibodyKD Validated MELK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3005 unconjugated Recombinant Antibody
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (Center) antibodyMELK 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 101-250) antibodyMELK 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 412-651) antibodyMELK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibodyMELK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the Melk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Melk antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
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别名
- Melk
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背景
- Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. Plays a key role in cell proliferation. Required for proliferation of embryonic and postnatal multipotent neural progenitors. Phosphorylates and inhibits BCL2L14. Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus. May also play a role in primitive hematopoiesis.
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UniProt
- Q61846
抗原
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