MEF2C 抗体 (AA 278-307)
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北京 101111
Quick Overview for MEF2C 抗体 (AA 278-307) (ABIN3031904)
抗原
See all MEF2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 278-307
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交叉反应 （详细）
- Expected species reactivity: Mouse, Bovine, Pig
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 278-307 from the human protein was used as the immunogen for this MEF2C antibody.
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亚型
- Ig Fraction
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anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 1-125) antibody
MEF2C 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6H2G2 unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) antibodyMEF2C 适用: 人 WB, IHC, IHC (p), IF, ICC, IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) antibodyMEF2C 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 365-394) antibodyMEF2C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser59) antibodyMEF2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser396) antibodyMEF2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser396) antibodyMEF2C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the MEF2C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MEF2C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
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别名
- MEF2C
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背景
- Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2. [UniProt]
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UniProt
- Q06413
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
抗原
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