MECP2 抗体 (AA 58-87)
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Quick Overview for MECP2 抗体 (AA 58-87) (ABIN3031763)
抗原
See all MECP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-87
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MeCP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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别名
- MeCP2
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背景
- MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]
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UniProt
- P51608
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途径
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
抗原
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