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MCM3 抗体 (AA 36-64)

This 兔 多克隆 antibody specifically detects MCM3 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN3031804
发货至: 中国
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Quick Overview for MCM3 抗体 (AA 36-64) (ABIN3031804)

抗原

See all MCM3 抗体
MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

适用

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人

宿主

  • 117
  • 19
  • 3
兔

克隆类型

  • 84
  • 55
多克隆

标记

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  • 7
  • 5
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This MCM3 antibody is un-conjugated

应用范围

  • 77
  • 64
  • 37
  • 22
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  • 14
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  • 10
  • 3
  • 2
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 36-64

    原理

    MCM3 Antibody

    预测反应

    Mouse,Bovine

    纯化方法

    Antigen affinity

    免疫原

    A portion of amino acids 36-64 from the human protein was used as the immunogen for this MCM3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles

    储存条件

    -20 °C

    储存方法

    Aliquot the MCM3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

    别名

    MCM3

    背景

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].

    UniProt

    P25205

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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