LRRK2 抗体 (C-Term)
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北京 101111
Quick Overview for LRRK2 抗体 (C-Term) (ABIN3031608)
抗原
See all LRRK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity purified
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免疫原
- This LRRK2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2171-2207 amino acids from the C-terminal region of human LRRK2.
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亚型
- Ig Fraction
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anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibody
LRRK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 2171-2207), (C-Term) antibodyLRRK2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal RB50924 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibodyLRRK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7199 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB07209 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7207 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 133AT1218 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 133AT720 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 133AT720 unconjugated
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应用备注
- Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LRRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
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别名
- LRRK2
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背景
- Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH , and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (,CNS),. Phosphorylates PRDX3. May also have GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
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UniProt
- Q5S007
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
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