Lamin B1 抗体 (AA 459-488)
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Quick Overview for Lamin B1 抗体 (AA 459-488) (ABIN3031587)
抗原
See all Lamin B1 (LMNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 459-488
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 459-488 from the human protein was used as the immunogen for this Lamin B1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Lamin B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Lamin B1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Lamin B1 (LMNB1)
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别名
- Lamin B1
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背景
- The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.
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UniProt
- P20700
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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