K-RAS 抗体 (AA 146-174)
Quick Overview for K-RAS 抗体 (AA 146-174) (ABIN3031120)
抗原
See all K-RAS (KRAS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 146-174
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 146-174 from the human protein was used as the immunogen for this KRAS antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the KRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-2000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the KRAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- K-RAS (KRAS) (GTPase Kras (KRAS))
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别名
- KRAS
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背景
- This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
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UniProt
- P01116
抗原
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