电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Kdm6b 抗体 (AA 954-987)

This anti-Kdm6b antibody (ABIN3031662) is a Rabbit Polyclonal antibody detecting Kdm6b in WB, ELISA. Suitable for Human, Mouse.
产品编号 ABIN3031662
发货至: 中国

Quick Overview for Kdm6b 抗体 (AA 954-987) (ABIN3031662)

抗原

See all Kdm6b 抗体
Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

适用

  • 46
  • 24
  • 10
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 48
  • 1
  • 1

克隆类型

  • 49
  • 1
多克隆

标记

  • 33
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Kdm6b antibody is un-conjugated

应用范围

  • 37
  • 23
  • 12
  • 7
  • 6
  • 5
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 954-987

    纯化方法

    Purified

    免疫原

    A portion of amino acids 954-987 from the mouse protein was used as the immunogen for this JMJD3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the JMJD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the JMJD3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

    别名

    JMJD3 (KDM6B)

    背景

    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

    UniProt

    Q5NCY0

    途径

    Warburg Effect
You are here:
Chat with us!