ISL1 抗体 (AA 156-185)
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Quick Overview for ISL1 抗体 (AA 156-185) (ABIN3031505)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-185
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交叉反应 (详细)
- Expected species reactivity: Rat, Chicken, Zebrafish
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 156-185 from the human protein was used as the immunogen for this ISL1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ISL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ISL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ISL1 (ISL LIM Homeobox 1 (ISL1))
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别名
- ISL1
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背景
- ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
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UniProt
- P61371
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途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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