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IRF9 抗体 (AA 75-104)

This anti-IRF9 antibody is a 兔 多克隆 antibody detecting IRF9 in WB, ELISA, IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN3031426
发货至: 中国

Quick Overview for IRF9 抗体 (AA 75-104) (ABIN3031426)

抗原

See all IRF9 抗体
IRF9 (Interferon Regulatory Factor 9 (IRF9))

适用

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人, 小鼠

宿主

  • 45
  • 7
  • 1

克隆类型

  • 46
  • 6
多克隆

标记

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This IRF9 antibody is un-conjugated

应用范围

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  • 15
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
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    • 2
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    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 75-104

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 75-104 from the human protein was used as the immunogen for this IRF9 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the IRF9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IRF9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IRF9 (Interferon Regulatory Factor 9 (IRF9))

    别名

    IRF9

    背景

    IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    UniProt

    Q00978

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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