MAVS 抗体 (AA 1-30)
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Quick Overview for MAVS 抗体 (AA 1-30) (ABIN3031815)
抗原
See all MAVS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1-30 from the mouse protein was used as the immunogen for this Ips-1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Ips-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Ips-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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别名
- Ips-1
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背景
- Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
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UniProt
- Q8VCF0
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途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
抗原
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