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MAVS 抗体 (AA 477-505)

MAVS 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031816
发货至: 中国
  • 抗原 See all MAVS 抗体
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    抗原表位
    • 15
    • 13
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 477-505
    适用
    • 48
    • 38
    • 4
    • 2
    • 1
    宿主
    • 69
    • 7
    克隆类型
    • 71
    • 5
    多克隆
    标记
    • 34
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAVS antibody is un-conjugated
    应用范围
    • 68
    • 36
    • 13
    • 13
    • 11
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 477-505 from the human protein was used as the immunogen for this MAVS antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAVS Primary Antibody
  • 应用备注
    Titration of the MAVS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the MAVS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    别名
    MAVS (MAVS 产品)
    别名
    CARDIF antibody, IPS-1 antibody, IPS1 antibody, VISA antibody, D430028G21Rik antibody, Visa antibody, cardif antibody, wu:fj20d04 antibody, zgc:158392 antibody, mitochondrial antiviral signaling protein antibody, MAVS antibody, Mavs antibody, mavs antibody
    背景
    Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI. These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA and IKKB which activate NFKB, or TBK1 and IKKE (IKBKE, MIM 605048), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB. For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF. For RIGI, the intermediary protein is mitochondria-bound IPS1.
    UniProt
    Q7Z434
    途径
    Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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