Integrin beta 7 抗体 (AA 737-765)
Quick Overview for Integrin beta 7 抗体 (AA 737-765) (ABIN3031382)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 737-765
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 737-765 from the human protein was used as the immunogen for this Integrin beta 7 antibody.
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亚型
- Ig Fraction
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anti-Integrin beta 7 (ITGB7) (AA 1-798) antibody
ITGB7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (AA 1-140) antibodyITGB7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (Internal Region) antibodyITGB7 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (AA 721-806) antibodyITGB7 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal FIB504 unconjugated
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS, IP, BR 宿主: 兔 Chimeric FIB27 unconjugated Recombinant Antibody
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS, IF, BR 宿主: 兔 Chimeric FIB504 unconjugated Recombinant Antibody
anti-Integrin beta 7 (ITGB7) (AA 401-505) antibodyITGB7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 8D3 unconjugated
anti-Integrin beta 7 (ITGB7) (AA 1-798) antibodyITGB7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Titration of the Integrin beta 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Integrin beta 7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Integrin beta 7 (ITGB7)
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别名
- Integrin beta 7
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背景
- Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.
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UniProt
- P26010
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途径
- Integrin Complex
抗原
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