This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000-4000
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the Integrin alpha 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
ITGA3
(Integrin, alpha 3 (ITGA3))
别名
Integrin alpha 3
背景
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.