电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ILK 抗体 (AA 391-421)

ILK 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031391
发货至: 中国
  • 抗原 See all ILK 抗体
    ILK (Integrin-Linked Kinase (ILK))
    抗原表位
    • 25
    • 24
    • 16
    • 15
    • 10
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 391-421
    适用
    • 149
    • 58
    • 52
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 158
    • 5
    • 1
    克隆类型
    • 156
    • 8
    多克隆
    标记
    • 63
    • 14
    • 14
    • 12
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    This ILK antibody is un-conjugated
    应用范围
    • 112
    • 86
    • 55
    • 40
    • 39
    • 20
    • 17
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Expected species reactivity: Rat, Bovine
    纯化方法
    Purified
    免疫原
    A portion of amino acids 391-421 from the human protein was used as the immunogen for this ILK2/ILK1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ILK Primary Antibody
  • 应用备注
    Titration of the ILK2/ILK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the ILK2/ILK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    ILK (Integrin-Linked Kinase (ILK))
    别名
    ILK2/ILK1 (ILK 产品)
    别名
    CG10504 antibody, CT29478 antibody, DmILK antibody, Dmel\\CG10504 antibody, ILK antibody, ilk antibody, l(3)78Ca antibody, p59 antibody, AA511515 antibody, ESTM24 antibody, zgc:65842 antibody, ILK-1 antibody, ILK-2 antibody, P59 antibody, p59ILK antibody, Integrin linked kinase antibody, integrin linked kinase antibody, integrin linked kinase S homeolog antibody, integrin-linked protein kinase antibody, integrin-linked kinase antibody, Ilk antibody, ILK antibody, ilk.S antibody, CpipJ_CPIJ016644 antibody, Bm1_20815 antibody, Tsp_07213 antibody, Tsp_07224 antibody, Tsp_15354 antibody, ilk antibody
    背景
    Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.
    UniProt
    Q13418
    途径
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
You are here:
客服