ILK 抗体 (AA 225-253)
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Quick Overview for ILK 抗体 (AA 225-253) (ABIN3031385)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-253
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 225-253 from the human protein was used as the immunogen for this ILK antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ILK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ILK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- ILK
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背景
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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