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IL-4 抗体 (AA 122-150)

The 兔 多克隆 anti-IL-4 antibody is suitable to detect IL-4 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC 和 FACS.
产品编号 ABIN3031478
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for IL-4 抗体 (AA 122-150) (ABIN3031478)

抗原

See all IL-4 (IL4) 抗体
IL-4 (IL4) (Interleukin 4 (IL4))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 122-150

    交叉反应 (详细)

    Expected species reactivity: Primate

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 122-150 from the human protein was used as the immunogen for this IL-4 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the IL-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL-4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL-4

    背景

    IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.

    UniProt

    P05112

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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