IL-4 抗体 (AA 122-150)
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北京 101111
Quick Overview for IL-4 抗体 (AA 122-150) (ABIN3031478)
抗原
See all IL-4 (IL4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-150
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 122-150 from the human protein was used as the immunogen for this IL-4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IL-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL-4 (IL4) (Interleukin 4 (IL4))
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别名
- IL-4
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背景
- IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.
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UniProt
- P05112
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
抗原
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