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IL-13 抗体 (AA 118-146)

This anti-IL-13 antibody is a 兔 多克隆 antibody detecting IL-13 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN3031449
发货至: 中国

Quick Overview for IL-13 抗体 (AA 118-146) (ABIN3031449)

抗原

See all IL-13 (IL13) 抗体
IL-13 (IL13) (Interleukin 13 (IL13))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-13 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 118-146

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL-13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    IL-13

    背景

    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

    UniProt

    P35225

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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