IL-13 抗体 (AA 118-146)
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Quick Overview for IL-13 抗体 (AA 118-146) (ABIN3031449)
抗原
See all IL-13 (IL13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-146
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL-13
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背景
- This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].
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UniProt
- P35225
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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