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IL-10 抗体 (AA 27-53)

This anti-IL-10 antibody is a 兔 多克隆 antibody detecting IL-10 in WB, IHC, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN3031441
发货至: 中国

Quick Overview for IL-10 抗体 (AA 27-53) (ABIN3031441)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 27-53

    交叉反应 (详细)

    Expected species reactivity: Primate

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL-10

    背景

    The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

    UniProt

    P22301

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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