IL-10 抗体 (AA 27-53)
Quick Overview for IL-10 抗体 (AA 27-53) (ABIN3031441)
抗原
See all IL-10 (IL10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-53
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL-10 (IL10) (Interleukin 10 (IL10))
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别名
- IL-10
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背景
- The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
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UniProt
- P22301
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
抗原
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