Glucagon 抗体 (AA 119-148)
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Quick Overview for Glucagon 抗体 (AA 119-148) (ABIN3031052)
抗原
See all Glucagon (GCG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-148
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纯化方法
- Purified
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免疫原
- A portion of amino acids 119-148 from the human protein was used as the immunogen for this Glucagon antibody.
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亚型
- IgG1 kappa
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应用备注
- Titration of the Glucagon antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Glucagon antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Glucagon (GCG)
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别名
- Glucagon
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背景
- The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
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UniProt
- P01275
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途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
抗原
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