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FLT3 抗体 (AA 33-64)

This anti-FLT3 antibody is a 兔 多克隆 antibody detecting FLT3 in WB, ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN3030975
发货至: 中国

Quick Overview for FLT3 抗体 (AA 33-64) (ABIN3030975)

抗原

See all FLT3 抗体
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 33-64

    纯化方法

    Purified

    免疫原

    A portion of amino acids 33-64 from the human protein was used as the immunogen for this FLT3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the FLT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FLT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    别名

    FLT3

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

    UniProt

    P36888

    途径

    RTK signaling
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