FGFR2 抗体 (AA 7-37)
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Quick Overview for FGFR2 抗体 (AA 7-37) (ABIN3030951)
抗原
See all FGFR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-37
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纯化方法
- Purified
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免疫原
- A portion of amino acids 7-37 from the human protein was used as the immunogen for this FGFR2 antibody.
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亚型
- Ig Fraction
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anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-100) antibody
FGFR2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-51), (N-Term) antibodyFGFR2 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01567 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 621-723) antibodyFGFR2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 245-345) antibodyFGFR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) antibodyFGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB17696 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 21-120) antibodyFGFR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (C-Term) antibodyFGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibodyFGFR2 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB15689 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 794-821) antibodyFGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibodyFGFR2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the FGFR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Immunofluorescence: 1:25,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the FGFR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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别名
- FGFR2
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背景
- FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.
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UniProt
- P21802
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
抗原
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