EZH1 抗体 (AA 393-422)
Quick Overview for EZH1 抗体 (AA 393-422) (ABIN3030806)
抗原
See all EZH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 393-422
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交叉反应 (详细)
- Expected species reactivity: Bovine
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纯化方法
- Purified
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免疫原
- A portion of amino acids 393-422 from the human protein was used as the immunogen for this EZH1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the EZH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the EZH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
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别名
- EZH1
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背景
- EZH1 encodes a protein of 747 amino acids that displays 55 % amino acid identity overall with the Drosophila homolog.1 The strong sequence conservation suggested potential roles for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that preserve heterochromatin stability. EZH1 is expressed as 2 major transcripts in all adult and fetal human tissues evaluated. Analysis of an EZH1 cDNA revealed an unusual splicing event involving EZH1 and a tandemly linked gene GPR2 and suggested a potential mechanism for modifying the EZH1 protein in the conserved C-terminal domain. The GPR2 gene maps to 17q21.1-q21.3 in the vicinity of the BRCA1 gene.
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UniProt
- Q92800
抗原
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