EPR1 抗体 (AA 308-337)
This anti-EPR1 antibody is a 兔 多克隆 antibody detecting EPR1 in WB 和 ELISA. Suitable for 人.
Quick Overview for EPR1 抗体 (AA 308-337) (ABIN3030795)
抗原
See all EPR1 抗体
EPR1
(Early-Phytochrome-Responsive1 (EPR1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This EPR1 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 308-337
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纯化方法
- Purified
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免疫原
- A portion of amino acids 308-337 from the human protein was used as the immunogen for this EPR1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the EPR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the EPR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
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别名
- EPR1
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背景
- Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
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UniProt
- Q14868
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途径
- Apoptosis, Cell Division Cycle
抗原
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