EPH Receptor B2 抗体 (AA 1021-1050)
Quick Overview for EPH Receptor B2 抗体 (AA 1021-1050) (ABIN3030826)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1021-1050
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纯化方法
- Purified
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免疫原
- A portion of amino acids 1021-1050 from the human protein was used as the immunogen for this EphB2 antibody.
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亚型
- Ig Fraction
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anti-EPH Receptor B2 (EPHB2) antibody
EPHB2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 48CT12-6-4 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 551-650) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 226-325) antibodyEPHB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 17-200) antibodyEPHB2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 2D12C6 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 1021-1050), (C-Term) antibodyEPHB2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB01652 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 261-465) antibodyEPHB2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (C-Term) antibodyEPHB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr331) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr317) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr298) antibodyEPHB2 适用: 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the EphB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the EphB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- EPH Receptor B2 (EPHB2)
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别名
- EphB2
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背景
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
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UniProt
- P29323
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途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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