Dnmt2 抗体 (AA 346-375)
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Quick Overview for Dnmt2 抗体 (AA 346-375) (ABIN3029268)
抗原
See all Dnmt2 (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 346-375
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纯化方法
- Purified
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免疫原
- A portion of amino acids 346-375 from the human protein was used as the immunogen for this Dnmt2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Dnmt2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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别名
- Dnmt2
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背景
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O14717
抗原
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