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DKK1 抗体

DKK1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030725
发货至: 中国
  • 抗原 See all DKK1 抗体
    DKK1 (Dickkopf Homolog 1 (DKK1))
    适用
    • 108
    • 32
    • 30
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 100
    • 11
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 91
    • 25
    多克隆
    标记
    • 62
    • 11
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK1 antibody is un-conjugated
    应用范围
    • 70
    • 52
    • 21
    • 13
    • 12
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    This DKK1 antibody was produced from a rabbit immunized with a recombinant protein of human DKK1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DKK1 Primary Antibody
  • 应用备注
    Titration of the DKK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-1:4000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the DKK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    DKK1 (Dickkopf Homolog 1 (DKK1))
    别名
    DKK1 (DKK1 产品)
    背景
    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt]
    UniProt
    O94907
    途径
    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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