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DKK1 抗体

The 兔 多克隆 anti-DKK1 antibody is suitable to detect DKK1 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN3030725
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for DKK1 抗体 (ABIN3030725)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DKK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antigen affinity purified

    免疫原

    This DKK1 antibody was produced from a rabbit immunized with a recombinant protein of human DKK1.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the DKK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-1:4000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DKK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    DKK1

    背景

    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt]

    UniProt

    O94907

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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