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DCLK2 抗体 (AA 167-196)

This anti-DCLK2 antibody is a 兔 多克隆 antibody detecting DCLK2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030772
发货至: 中国

Quick Overview for DCLK2 抗体 (AA 167-196) (ABIN3030772)

抗原

See all DCLK2 抗体
DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

适用

  • 27
  • 13
  • 3

宿主

  • 25
  • 2

克隆类型

  • 25
  • 2
多克隆

标记

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DCLK2 antibody is un-conjugated

应用范围

  • 19
  • 13
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-196

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 167-196 from the human protein was used as the immunogen for this DCLK2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the DCLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DCLK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

    别名

    DCLK2

    背景

    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

    UniProt

    Q8N568
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