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Cyclin D2 抗体 (AA 1-30)

This anti-Cyclin D2 antibody is a 兔 多克隆 antibody detecting Cyclin D2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030593
发货至: 中国

Quick Overview for Cyclin D2 抗体 (AA 1-30) (ABIN3030593)

抗原

See all Cyclin D2 (CCND2) 抗体
Cyclin D2 (CCND2)

适用

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  • 48
  • 37

宿主

  • 68
  • 33

克隆类型

  • 71
  • 30
多克隆

标记

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This Cyclin D2 antibody is un-conjugated

应用范围

  • 68
  • 37
  • 17
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Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 12
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    AA 1-30

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin D2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Cyclin D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Cyclin D2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cyclin D2 (CCND2)

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

    UniProt

    P30279

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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