Cyclin D2 抗体 (AA 1-30)
-
- 抗原 See all Cyclin D2 (CCND2) 抗体
- Cyclin D2 (CCND2)
-
抗原表位
- AA 1-30
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Cyclin D2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin D2 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CCND2 Primary Antibody
-
-
- 应用备注
- Titration of the Cyclin D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the Cyclin D2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- Cyclin D2 (CCND2)
- Abstract
- CCND2 产品
- 背景
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
- UniProt
- P30279
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
-