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Cyclin D1 抗体 (AA 203-238)

This anti-Cyclin D1 antibody is a 兔 多克隆 antibody detecting Cyclin D1 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN3029709
发货至: 中国

Quick Overview for Cyclin D1 抗体 (AA 203-238) (ABIN3029709)

抗原

See all Cyclin D1 (CCND1) 抗体
Cyclin D1 (CCND1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin D1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 203-238

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 203-238 from the human protein was used as the immunogen for this Cyclin D antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Cyclin D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Cyclin D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cyclin D1 (CCND1)

    背景

    CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.

    UniProt

    P24385

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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