CUX1 抗体 (AA 1347-1374)
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Quick Overview for CUX1 抗体 (AA 1347-1374) (ABIN3030580)
抗原
See all CUX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1347-1374
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CUX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CUX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CUX1 (Cut-Like Homeobox 1 (CUX1))
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别名
- CUX1
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背景
- CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). [UniProt]
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UniProt
- P39880
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途径
- Cellular Glucan Metabolic Process
抗原
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