Claudin 2 抗体 (AA 135-164)
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Quick Overview for Claudin 2 抗体 (AA 135-164) (ABIN3030535)
抗原
See all Claudin 2 (CLDN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-164
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交叉反应 (详细)
- Expected species reactivity: Mouse, Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Claudin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Claudin 2 (CLDN2)
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背景
- Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]
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UniProt
- P57739
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途径
- Hepatitis C
抗原
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