CDX2 抗体 (AA 1-30)
Quick Overview for CDX2 抗体 (AA 1-30) (ABIN3030336)
抗原
See all CDX2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-30
-
交叉反应 （详细）
- Expected species reactivity: Mouse
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this CDX2 antibody.
-
亚型
- Ig Fraction
-
-
anti-Caudal Type Homeobox 2 (CDX2) antibody
CDX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-180) antibodyCDX2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B4C1 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-313) antibodyCDX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 176-303) antibodyCDX2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G9B9 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 150-249) antibodyCDX2 适用: 人 ELISA, Coat, IHC (f), ISt 宿主: 小鼠 Monoclonal CDX2-1690 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, Synthetic IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Caudal Type Homeobox 2 (CDX2) antibodyCDX2 适用: 人 IHC (f), ISt 宿主: 小鼠 Monoclonal CDX2-2214 unconjugated
anti-Caudal Type Homeobox 2 (CDX2) (AA 1-60) antibodyCDX2 适用: 人, 小鼠, 大鼠, 猴, Cow, 马, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Titration of the CDX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CDX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- CDX2 (Caudal Type Homeobox 2 (CDX2))
-
别名
- CDX2
-
背景
- The caudal type homeo box transcription factors 1 (CDX1) and 2 (CDX2) are candidates for directing intestinal development, differentiation, and maintenance of the intestinal phenotype. CDX1 and CDX2 expression is widely present in the human intestinal and colonic mucosae, but not in the gastric mucosa, suggesting a possible role in the terminal differentiation of the intestine. Increased CDX2 expression is associated with chronic atrophic gastritis. Detectable expression of CDX2 precedes expression of CDX1 during the progression of intestinal metaplasia, thus expression of CDX2 may trigger the initiation and development of intestinal metaplasia. Markedly reduced or absent CDX2 expression was noted by immunohistochemistry in 13 of 15 (87 % ) large cell minimally differentiated carcinomas (LCMDCs), whereas only 1 of the 25 (4 %) differentiated adenocarcinomas (DACs) showed reduced CDX2 expression. Thus, a significant decrease in human CDX1 and/or CDX2 expression may be associated with colorectal tumorigenesis.
-
UniProt
- Q99626
-
途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
抗原
-
