CDC6 抗体 (AA 32-61)
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北京 101111
Quick Overview for CDC6 抗体 (AA 32-61) (ABIN3030464)
抗原
See all CDC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-61
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 32-61 from the human protein was used as the immunogen for this CDC6 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CDC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CDC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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别名
- CDC6
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背景
- Human CDC6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
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UniProt
- Q99741
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途径
- DNA Replication, Synthesis of DNA
抗原
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