CD68 抗体 (AA 209-237)
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Quick Overview for CD68 抗体 (AA 209-237) (ABIN3030411)
抗原
See all CD68 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 209-237
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 209-237 from the human protein was used as the immunogen for this CD68 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD68 (CD68 Molecule (CD68))
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别名
- CD68
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背景
- This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
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UniProt
- P34810
抗原
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