CD46 抗体 (AA 317-343)
Quick Overview for CD46 抗体 (AA 317-343) (ABIN3030405)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 317-343
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 317-343 from the human protein was used as the immunogen for this CD46 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CD46 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD46 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD46
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别名
- CD46
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背景
- CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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