CD11b 抗体 (AA 253-282)
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Quick Overview for CD11b 抗体 (AA 253-282) (ABIN3031364)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 253-282
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD11b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- CD11b
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背景
- CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
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UniProt
- P11215
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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