CCR8 抗体 (AA 290-317)
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Quick Overview for CCR8 抗体 (AA 290-317) (ABIN3030499)
抗原
See all CCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-317
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 290-317 from the human protein was used as the immunogen for this CCR8 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CCR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CCR8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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别名
- CCR8
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背景
- CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
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UniProt
- P51685
抗原
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