CCL2 抗体 (AA 62-89)
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Quick Overview for CCL2 抗体 (AA 62-89) (ABIN3030482)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 62-89
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Purified
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免疫原
- A portion of amino acids 62-89 from the human protein was used as the immunogen for this CCL2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CCL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CCL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- CCL2
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背景
- Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
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UniProt
- P13500
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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