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CASP5 抗体 (AA 162-191)

The 兔 多克隆 anti-CASP5 antibody (ABIN3030309) specifically detects CASP5 in WB, ELISA, IHC 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN3030309
发货至: 中国
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Quick Overview for CASP5 抗体 (AA 162-191) (ABIN3030309)

抗原

See all CASP5 抗体
CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CASP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 162-191

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 162-191 from the human protein was used as the immunogen for this Caspase-5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Caspase-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Caspase-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

    别名

    Caspase-5

    背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

    UniProt

    P51878

    途径

    Inflammasome
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