Caspase 10 抗体 (AA 164-192)
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Quick Overview for Caspase 10 抗体 (AA 164-192) (ABIN3030290)
抗原
See all Caspase 10 (CASP10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-192
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纯化方法
- Purified
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免疫原
- A portion of amino acids 164-192 from the human protein was used as the immunogen for this Caspase-10 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Caspase-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Caspase-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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别名
- Caspase-10
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背景
- CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
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UniProt
- Q92851
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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