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BTK 抗体 (AA 209-239)

Name: BTK 抗体 (AA 209-239)
SKU: ABIN3030211
Availability: OutOfStock

This anti-BTK antibody is a 兔多克隆 antibody detecting BTK in WB, ELISA, IHC 和 IF. Suitable for 人.

BTK antibody used in western blot to detect BTK in Ramos cell lysate (BTK 抗体 (AA 209-239))

Confocal immunofluorescent analysis of BTK antibody with 293 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (BTK 抗体 (AA 209-239))

IHC analysis of FFPE human breast carcinoma tissue stained with the BTK antibody (BTK 抗体 (AA 209-239))

IHC

5 images

产品编号 ABIN3030211

发货至: 中国

Quick Overview for BTK 抗体 (AA 209-239) (ABIN3030211)

抗原

See all BTK 抗体

BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

适用

人

宿主

兔

克隆类型

多克隆

标记

This BTK antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product BTK Primary Antibody

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AA 209-239

纯化方法

Purified

免疫原

A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.

亚型

Ig Fraction
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 30-240) antibody
BTK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) antibody
BTK 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 27-55) antibody
BTK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (pSer180) antibody
BTK 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 254-443) antibody
BTK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 91-387) antibody
BTK 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (C-Term) antibody
BTK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) antibody
BTK 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7F12H4 unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (pTyr223) antibody
BTK 适用: 人, 小鼠 ELISA, IF (cc), IF (p), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (pTyr551) antibody
BTK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the BTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the BTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

别名

BTK

背景

BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Defects in BTK are the cause of X-linked agammaglobulinemia type 1 (XLA). XLA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections like otitis, conjunctivitis, dermatitis, sinusitis or fatal sepsis or meningitis within the first years of life.

UniProt

Q06187

途径

Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling