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BIM 抗体 (AA 130-165)

This anti-BIM antibody is a 兔 多克隆 antibody detecting BIM in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN3030147
发货至: 中国

Quick Overview for BIM 抗体 (AA 130-165) (ABIN3030147)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

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  • 57
  • 5
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  • 1
  • 1

宿主

  • 108
  • 9
  • 3
  • 1

克隆类型

  • 93
  • 28
多克隆

标记

  • 69
  • 9
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  • 1
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This BIM antibody is un-conjugated

应用范围

  • 82
  • 48
  • 46
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  • 13
  • 5
  • 5
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 15
    • 7
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    • 6
    • 6
    • 5
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    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-165

    纯化方法

    Purified

    免疫原

    A portion of amino acids 130-165 from the human protein was used as the immunogen for this Bim antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Bim antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Bim antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    Bim

    背景

    Bim belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bim contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection.

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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