BACE1 抗体 (AA 476-501)
Quick Overview for BACE1 抗体 (AA 476-501) (ABIN3030158)
抗原
See all BACE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 476-501
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交叉反应 (详细)
- Expected species reactivity: Rat, Bovine
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纯化方法
- Purified
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免疫原
- A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BACE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- BACE
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背景
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
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UniProt
- P56817
抗原
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