Aurora Kinase B 抗体 (AA 84-111)
Quick Overview for Aurora Kinase B 抗体 (AA 84-111) (ABIN3030074)
抗原
See all Aurora Kinase B (AURKB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-111
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Aurkb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Aurkb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Aurora Kinase B (AURKB)
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别名
- Aurkb
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背景
- Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1 (By similarity).
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UniProt
- O70126
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途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
抗原
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