ATG13 抗体 (AA 1-30)
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北京 101111
Quick Overview for ATG13 抗体 (AA 1-30) (ABIN3030086)
抗原
See all ATG13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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交叉反应 (详细)
- Expected species reactivity: Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this ATG13 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ATG13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ATG13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ATG13 (Autophagy Related 13 (ATG13))
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别名
- ATG13
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背景
- ATG13 is an autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. [UniProt]
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UniProt
- O75143
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途径
- PI3K-Akt Signaling, Autophagy
抗原
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